Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report

Autor: Janne Nordberg, Tero Taiminen, Lauri Virtanen, Satu K. Jääskeläinen, Noora M. Scheinin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Brain Stimulation, Vol 14, Iss 6, Pp 1467-1469 (2021)
Druh dokumentu: article
ISSN: 1935-861X
DOI: 10.1016/j.brs.2021.09.011
Popis: Background: Inhibitory low frequency repetitive transcranial magnetic stimulation (rTMS) of the temporo-parietal area has been applied to treat both auditory verbal hallucinations as well as tinnitus. Objective: We hypothesized that 1 Hz rTMS to the left temporoparietal junction (TPJ) may be beneficial in alleviating musical hallucinations (MH), another condition with auditory experiences in the absence of an external source. Methods: Here we describe a patient with almost insufferable life-long MH with comorbid depression, who received inhibitory rTMS to the left TPJ as well as the right dorsolateral prefrontal cortex (DLPFC). Results: The intrusiveness and frequency of her MH as well as her depressive symptoms alleviated quickly and substantially, and once-a-week maintenance therapy with rTMS seemed to preserve this amelioration. Future studies will hopefully reveal whether this is a viable treatment approach for other patients suffering from MH with or without comorbid depression.
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