Psychomotor Development in Cri du Chat Syndrome: Comparison in Two Italian Cohorts with Different Rehabilitation Methods

Autor: Andrea Guala, Marianna Spunton, Fabio Tognon, Marilena Pedrinazzi, Luisa Medolago, Paola Cerutti Mainardi, Silvia Spairani, Michela Malacarne, Enrico Finale, Mario Comelli, Cesare Danesino
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: The Scientific World Journal, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2356-6140
1537-744X
DOI: 10.1155/2016/3125283
Popis: The Cri du Chat syndrome (CdC) is a rare genetic disorder caused by variable size deletions of the short arm of chromosome 5 (5p−). It is well known that home-reared patients show better performances as compared to institutionalised cases, and it was reported that continuous educational intervention can ameliorate their performances. To assess the efficacy of educational intervention and to develop new CdC oriented programs of rehabilitation, we compare the results obtained for many developmental skills in two groups of CdC patients undergoing two different rehabilitation programs. Using data on the development of a group of CdC patients obtained by validated Italian translation for the Denver Developmental Screening Test II, we compared a group of 13 patients undergoing an educational program developed for CdC patients, the Mayer Project (MP), with a second group of 15 cases in whom caring was not specifically oriented. A positive impact of the MP was reported by parents, observing an improvement in social skills obtained, even if no significant differences were observed when the items of the Denver Test are studied. The need for personalized care in CdC patients and the choice of different methods to compare the results are also discussed.
Databáze: Directory of Open Access Journals
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