| Autor: |
Alessandro E. Vento, Fabrizio Schifano, Federica Gentili, Francesco Pompei, John M. Corkery, Georgios D. Kotzalidis, Paolo Girardi |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Annali dell'Istituto Superiore di Sanità, Vol 49, Iss 4, Pp 402-405 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
0021-2571 |
| DOI: |
10.4415/ANN_13_04_14 |
| Popis: |
BACKGROUND AND OBJECTIVE: Despite animal studies having shown a generalisation of the bupropion cue to cocaine, this drug has been used in cocaine abuse with mixed results. We here aimed at describing two cases which contradict current knowledge. CASE REPORTS: We describe two cases of former cocaine abusers who reported a cocaine-like sensation upon taking bupropion. Bupropion improved patients' depression without any increase in cocaine craving. One of the patients increased without doctor consultation his dose on an as needed basis. CONCLUSIONS: The issue of bupropion cue generalisation to cocaine needs further elucidation. People with past cocaine addiction need to be informed on the potential of bupropion to elicit cocaine-like cues and be invited to adhere to medical prescription, because bupropion has been associated with fatalities in some cases. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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