| Autor: |
Min Cheng, Junjie Yang, Xiaoqi Zhao, Eric Zhang, Qiutang Zeng, Yang Yu, Liu Yang, Bangwei Wu, Guiwen Yi, Xiaobo Mao, Kai Huang, Nianguo Dong, Min Xie, Nita A. Limdi, Sumanth D. Prabhu, Jianyi Zhang, Gangjian Qin |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-08895-7 |
| Popis: |
During myocardial infarction, microRNAs (myo-miRs) are released into the circulation. Here Cheng et al. show that myo-miRs carried in exosomes are transferred to the bone marrow (BM), downregulate expression of CXCR4 in mononuclear cells, and increase the number of circulating BM progenitor cells, thus orchestrating a systemic response to myocardial injury. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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