Autor: |
Min Seong Kim, Tae Joo Jeon, Ji Young Park, Jeongmin Choi, Won Chang Shin, Seong Eun Park, Ji-Young Seo, Young Moon Kim |
Jazyk: |
English<br />Korean |
Rok vydání: |
2017 |
Předmět: |
|
Zdroj: |
The Korean Journal of Gastroenterology, Vol 70, Iss 2, Pp 96-102 (2017) |
Druh dokumentu: |
article |
ISSN: |
1598-9992 |
DOI: |
10.4166/kjg.2017.70.2.96 |
Popis: |
Background/Aims: Elevated carbohydrate antigen (CA) 19-9 level may be unable to differentiate between benign and malignant pancreatobiliary disease with obstructive jaundice. The study aims to determine the clinical interpretation and the diagnostic value of CA 19-9 level in pancreatobiliary diseases with coexistent obstructive jaundice. Methods: We retrospectively reviewed the data of 981 patients who underwent biliary drainage due to obstructive jaundice following pancreatobiliary disease at Sanggye Paik Hospital for 5 years. 114 patients with serial follow-up data for CA 19-9 level were included in this study (80 patients with malignancy and 34 patients with benign diseases). We compared the levels of CA 19-9 levels and the biochemical value before and after biliary drainage. Results: The rate of CA 19-9 elevation (>37 U/mL) was significantly different between the benign group and the malignant group (59% vs. 90%, p=0.001). Despite the decrease in serum bilirubin after biliary drainage, CA 19-9 levels remained elevated in 12% of patients in the benign group and in 63% of patients in the malignant group (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|