Progress in germline stem cell transplantation in mammals and the potential usage

Autor:	Wen Zhang, Ruotian Nie, Yihui Cai, Wenhai Xie, Kang Zou
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Chemotherapy Fertility Homing efficiency Livestock Three-dimensional culture Gynecology and obstetrics RG1-991 Reproduction QH471-489
Zdroj:	Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-9 (2022)
Druh dokumentu:	article
ISSN:	1477-7827
DOI:	10.1186/s12958-022-00930-5
Popis:	Abstract Germline stem cells (GSCs) are germ cells with the capacities of self-renewal and differentiation into functional gametes, and are able to migrate to their niche and reconstitute the fertility of recipients after transplantation. Therefore, GSCs transplantation is a promising technique for fertility recovery in the clinic, protection of rare animals and livestock breeding. Though this novel technique faces tremendous challenges, numerous achievements have been made after several decades’ endeavor. This review summarizes the current knowledge of GSCs transplantation and its utilization in mammals, and discusses the application prospect in reproductive medicine and animal science.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7c05ab1bba55436393ce9ed8af08fcfd Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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