| Autor: |
Al-Fatlawi Manar Mohammed Hadi, Al-Ammar Mahdi Hussain, Al-Manssori Yasir Lafta Hassoun |
| Jazyk: |
English<br />French |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BIO Web of Conferences, Vol 84, p 03019 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2117-4458 |
| DOI: |
10.1051/bioconf/20248403019 |
| Popis: |
The study aimed to evaluate the gene expression of genes (TLR-4,NOD-2) in patients of Otitis media and healthy persons. This finding included 50 samples that collected from healthy subject and 100 samples from a patients suffering from otitis media who attended Al-Sadr Medical City (ENT Department) in Al-Najaf Governorate during the period from February 2022 to June 2022. The samples had an average age ranging from 5 to 70 years. The gene expression of these genes among those suffering from Otitis media and healthy individuals have been investigated in this case-control research. Using a PCR technology. polymerase chain reactions were carried out to amplify each sample for the patient and control groups. The results of the molecular study (gene expression) showed a high significant increase in the level of gene expression in patients for the two genes NOD-2, TLR-4 genes (14.78 ± 2.369, 16.42 ± 3.158), respectively, with a significant difference at P≤0.05. TLR-4, NOD-2 as used as a molecular diagnosis Otitis Media patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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