Whole Cells as Biocatalysts in Organic Transformations

Autor: Fabián Garzón-Posse, Liliana Becerra-Figueroa, José Hernández-Arias, Diego Gamba-Sánchez
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Molecules, Vol 23, Iss 6, p 1265 (2018)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules23061265
Popis: Currently, the power and usefulness of biocatalysis in organic synthesis is undeniable, mainly due to the very high enantiomeric excess reached using enzymes, in an attempt to emulate natural processes. However, the use of isolated enzymes has some significant drawbacks, the most important of which is cost. The use of whole cells has emerged as a useful strategy with several advantages over isolated enzymes; for this reason, modern research in this field is increasing, and various reports have been published recently. This review surveys the most recent developments in the enantioselective reduction of carbon-carbon double bonds and prochiral ketones and the oxidation of prochiral sulfides using whole cells as biocatalytic systems.
Databáze: Directory of Open Access Journals
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