Eutectic Salt Catalyzed Environmentally Benign and Highly Efficient Biginelli Reaction

Autor: Najmadin Azizi, Sahar Dezfuli, Mohmmad Mahmoodi Hahsemi
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: The Scientific World Journal, Vol 2012 (2012)
Druh dokumentu: article
ISSN: 1537-744X
DOI: 10.1100/2012/908702
Popis: A simple deep eutectic solvent based on tin (II) chloride was used as a dual catalyst and environmentally benign reaction medium for an efficient synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives, from aromatic and aliphatic aldehydes, 1,3-dicarbonyl compounds, and urea in good-to-excellent yields and short reaction time. This simple ammonium deep eutectic solvent, easily synthesized from choline chloride and tin chloride, is relatively inexpensive and recyclable, making it applicable for industrial applications.
Databáze: Directory of Open Access Journals