Optimization of Resolving Power, Fragmentation, and Mass Calibration in an Orbitrap Spectrometer for Analysis of 24 Pesticide Metabolites in Urine
Autor: | Pablo Dualde, Clara Coscollà, Agustin Pastor, Vicent Yusà |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | International Journal of Analytical Chemistry, Vol 2019 (2019) |
Druh dokumentu: | article |
ISSN: | 1687-8760 1687-8779 |
DOI: | 10.1155/2019/1917369 |
Popis: | Mass spectrometer parameters such as Resolving Power, type of fragmentation, and mass calibration mode were optimized in the analysis of 24 pesticide metabolites in human urine using Ultra-High Pressure Liquid Chromatography coupled to Orbitrap High-Resolution Mass Spectrometer (UHPLC-HRMS). The best results were achieved with a Resolving Power of 25,000 FWHM and by applying Collision Induced Dissociation fragmentation mode (40 eV). |
Databáze: | Directory of Open Access Journals |
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