Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation.

Autor: Annabel T Olson, Yuqi Kang, Anushka M Ladha, Songli Zhu, Chuan Bian Lim, Behnam Nabet, Michael Lagunoff, Taranjit S Gujral, Adam P Geballe
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: PLoS Pathogens, Vol 19, Iss 9, p e1011169 (2023)
Druh dokumentu: article
ISSN: 1553-7366
1553-7374
DOI: 10.1371/journal.ppat.1011169&type=printable
Popis: Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in patients with AIDS. KS tumor cells harbor KSHV predominantly in a latent form, while typically
Databáze: Directory of Open Access Journals
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