Comparison of cardiovascular disease risk in women with and without breast cancer: secondary data analysis with the 2014–2018 korean national health and nutrition examination survey

Autor: Seongmi Choi, Na-Jin Park, Mihui Kim, Kijun Song, JiYeon Choi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Public Health, Vol 23, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-023-16063-2
Popis: Abstract Background Aging breast cancer survivors may be at an elevated risk of cardiovascular disease (CVD), but little is known about CVD risk assessment and breast cancer in Korean women. We hypothesized that Korean breast cancer survivors would have higher risks of future CVD within the next 10 years (i.e., Framingham Risk Score [FRS]) than women without cancer. Objectives (1) To compare FRS-based CVD risks in women with and without breast cancer based on propensity score matching; and (2) To explore adiposity-related measures in relation to FRS in Korean women with breast cancer. Methods Using the cross-sectional data from the 2014–2018 Korean National Health and National Survey (KNHANES), we identified 136 women with breast cancer aged 30–74 years who had no other cancer and no CVD. The comparison group of 544 women with no cancer were selected by 1:4 nearest-neighbor propensity score matching based on breast cancer diagnosis. CVD risk was assessed by FRS based on multiple traditional risk factors (e.g., cholesterol, blood pressure, diabetes, and smoking). Adiposity was measured by physical examination, including body mass index (BMI) and waist-to-height ratio (WHtR). Physical activity and health behaviors were assessed by self-reports. Results Women with breast cancer (mean age of 57 years) had similar FRS levels at a low-risk category (
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