Transition-metal-free synthesis of triarylmethanes via Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives

Autor: Xinlei Fu, Longhui Wu, Xiaohua Guo, Kai Yang, Zhaowen Liu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Saudi Chemical Society, Vol 28, Iss 4, Pp 101883- (2024)
Druh dokumentu: article
ISSN: 1319-6103
DOI: 10.1016/j.jscs.2024.101883
Popis: A facile, transition-metal-free, HFIP-promoted method for the synthesis of triarylmethanes through direct Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives has been described, which allows for efficient synthesis of triarylmethanes containing imidazo[1,2-a]pyridines in good to satisfactory yields at room temperature. This transformation features simple operation, excellent functional group tolerance, and a broad substrate scope.
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