Gestational Diabetes Mellitus and Antenatal Corticosteroid Therapy—A Narrative Review of Fetal and Neonatal Outcomes

Autor: Ivana R. Babović, Jelena Dotlić, Radmila Sparić, Miljana Z Jovandaric, Mladen Andjić, Mirjana Marjanović Cvjetićanin, Slavica Akšam, Jovan Bila, Lidija Tulić, Dušica Kocijančić Belović, Vera Plešinac, Jovana Plesinac
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Clinical Medicine, Vol 12, Iss 1, p 323 (2022)
Druh dokumentu: article
ISSN: 2077-0383
DOI: 10.3390/jcm12010323
Popis: Background: There, we review the pathogenesis of gestational diabetes mellitus (GDM), its influence on fetal physiology, and neonatal outcomes, as well as the usage of antenatal corticosteroid therapy (ACST) in pregnancies complicated by GDM. Methods: MEDLINE and PubMed search was performed for the years 1990–2022, using a combination of keywords on such topics. According to the aim of the investigation, appropriate articles were identified and included in this narrative review. Results: GDM is a multifactorial disease related to unwanted pregnancy course and outcomes. Although GDM has an influence on the fetal cardiovascular and nervous system, especially in preterm neonates, the usage of ACST in pregnancy must be considered taking into account maternal and fetal characteristics. Conclusions: GDM has no influence on neonatal outcomes after ACST introduction. The ACST usage must be personalized and considered according to its gestational age-specific effects on the developing fetus.
Databáze: Directory of Open Access Journals
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