Efficacy of low-concentration atropine (0.01%) eye drops for prevention of axial myopic progression in premyopes

Autor: Jitendra Jethani
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Indian Journal of Ophthalmology, Vol 70, Iss 1, Pp 238-240 (2022)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/ijo.IJO_1462_21
Popis: Purpose: Low-concentration atropine (LCA; 0.01%) is known to reduce the progression of myopia in axial myopes. The purpose of this study was to understand the role of LCA in premyopic children in preventing progression. Methods: A randomized case–control study of known premyopes was done between the use of LCA and no intervention. A total of 30 children were included in both groups. Results: The mean age in the LCA group was 7.7 ± 2.1 years (5–12 years), and in the control group, it was 7.2 ± 1.9 years (4–12 years). The mean baseline progression per year in the LCA group (before starting the eye drops) was − 0.72 ± 0.3 D, and in the control group, it was − 0.69 ± 0.4 D. At the end of the first year, the mean progression in the LCA group was − 0.31 ± 0.3 D versus − 0.76 ± 0.4 D, and the axial length increase was 0.12 ± 0.1 mm in the LCA group and 0.21 ± 0.2 mm in the control group. At the end of the second year, the mean progression compared with the baseline in the LCA group was − 0.6 ± 0.3 D versus − 1.75 ± 0.4 D, and the axial length showed an increase from baseline in the LCA group by 0.21 ± 0.2 mm, and in the control group, the increase was 0.48 ± 0.2 mm in 2 years. Conclusion: Low-concentration eye drops (0.01%) work in preventing the progression of axial myopia in premyopic children.
Databáze: Directory of Open Access Journals
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