Treatment of lateral epicondylitis with platelet-rich plasma, glucocorticoid, or saline. A comparative study

Autor: Mahmoud El Tayeb Nasser, Ahmed Z El Yasaki, Reem M Ezz El Mallah, Amal S.M. Abdelazeem
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Egyptian Rheumatology and Rehabilitation, Vol 44, Iss 1, Pp 1-10 (2017)
Druh dokumentu: article
ISSN: 1110-161X
2090-3235
DOI: 10.4103/1110-161X.200838
Popis: Background Lateral epicondylitis (LE) is the most common overuse syndrome and related to excessive wrist extension, known as tendonitis of the extensor muscles of the forearm, and refers to pain and tenderness over the lateral epicondyle of the humerus. Local corticosteroid injection has short-term benefits in pain reduction, global improvement, and grip strength compared with placebo (saline or lidocaine) and other conservative treatments. Autologous platelet-rich plasma (PRP) injection has gained popularity within the sports medicine literature because of its presumed safety and ease of use as a potential treatment for any musculoskeletal problems by inducing cell proliferation and promoting the healing process. This thesis was carried out to assess the effectiveness of different types of injections (PRP, glucocorticoid, and saline) in improving pain and function in patients with LE. Patients and methods This study included 45 patients with LE (more than 3 months) between 31 and 58 years of age. All patients were subjected to assessment of history, clinical examination by the visual analogue scale (VAS), functional assessment by patient-rated tennis elbow evaluation (PRTEE), laboratory investigations, and ultrasonography assessment of the elbow. All the patients were divided randomly into three groups: group I received a saline injection, group II received a PRP injection, and group III received a corticosteroid injection. Patients were reassessed clinically and by ultrasound after 3 months. Results The present study showed that VAS and PRTEE scores were highly significantly reduced after injection in group II than group I and group III. Moreover, the reductions in VAS and PRTEE were highly significantly different in group III in comparison with group I. In terms of ultrasonographic changes and reduction in tenderness, there was a highly significant improvement in group II than group I and group III. Moreover, the reduction was highly significantly different in group III than group I. Conclusion PRP injection may offer several therapeutic advantages over corticosteroid injection.
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