Lower serum LH level was related to poor embryo quality and adverse pregnancy outcomes in fixed GnRH antagonist protocol with estradiol pretreatment

Autor:	Ying Chen, Yizhe Li, Xu Li, Linhong Liu, Zhen Liu, Wenwu Gui, Xiru Liu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Luteinizing hormone pregnancy outcomes GnRH antagonist estradiol pretreatment in vitro fertilization and embryo transfer Gynecology and obstetrics RG1-991 Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Gynecological Endocrinology, Vol 40, Iss 1 (2024)
Druh dokumentu:	article
ISSN:	09513590 1473-0766 0951-3590
DOI:	10.1080/09513590.2024.2409147
Popis:	Objective To disclose the relationships between serum LH and reproductive outcomes in Gonadotropin-releasing hormone (GnRH) antagonist protocol pretreated with luteal estradiol.Methods 371 patients, pretreated with estradiol, followed the GnRH antagonist protocol. They were divided into four groups based on the quartiles of serum LH levels on the day of gonadotropin (Gn) initiation(LHGI) and trigger (LHtrigger). Data on various pregnancy outcomes were collected.Results As serum LHGI increased, anti-Müllerian hormone (AMH) level, antral follicle count (AFC), LHtrigger, estradiol (E2) and P on the trigger day, E2/oocytes, and oocyte numbers increased and peaked in Q4, while Gn dose decreased. Good-quality embryo and blast formation rates increased and peaked in Q3. LHGI
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7ba634a96a27440287560058e43ee396 Zobrazit plný text záznamu View record in DOAJ