Role of intercellular adhesion molecules in the development of the endometrial neoplasias

Autor: E E Shelokova, V A Kovyazin, I I Babichenko
Jazyk: English<br />Russian
Rok vydání: 2011
Předmět:
Zdroj: RUDN Journal of Medicine, Vol 0, Iss 3, Pp 26-30 (2011)
Druh dokumentu: article
ISSN: 2313-0245
2313-0261
Popis: In article the processes of intercellular adhesion in unchanged proliferating endometrium, hyperplasia and adenocarcinoma are surveyed. Expression E-kadherin, β-katenin and claudin-1 at different stages of epithelial neoplastic transformation of endometrium by immunohistochemical method had been estimated. The role of key proteins Wnt-signaling pathway and Claudine-1 in the development of malignant transformation of glandular cells of endometrium was established.
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