Role of intercellular adhesion molecules in the development of the endometrial neoplasias
Autor: | E E Shelokova, V A Kovyazin, I I Babichenko |
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Jazyk: | English<br />Russian |
Rok vydání: | 2011 |
Předmět: | |
Zdroj: | RUDN Journal of Medicine, Vol 0, Iss 3, Pp 26-30 (2011) |
Druh dokumentu: | article |
ISSN: | 2313-0245 2313-0261 |
Popis: | In article the processes of intercellular adhesion in unchanged proliferating endometrium, hyperplasia and adenocarcinoma are surveyed. Expression E-kadherin, β-katenin and claudin-1 at different stages of epithelial neoplastic transformation of endometrium by immunohistochemical method had been estimated. The role of key proteins Wnt-signaling pathway and Claudine-1 in the development of malignant transformation of glandular cells of endometrium was established. |
Databáze: | Directory of Open Access Journals |
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