Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions

Autor: Zhan Gao, Zhicai Li, Xiaowei Li, Jun Xiao, Cuiying Li
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2296-634X
DOI: 10.3389/fcell.2023.1161541
Popis: Red blood cells (RBCs) produced in vitro have the potential to alleviate the worldwide demand for blood transfusion. Hematopoietic cell differentiation and proliferation are triggered by numerous cellular physiological processes, including low oxygen concentration (
Databáze: Directory of Open Access Journals