Linkage of blood cell division cycle 42 with T helper cells, and their correlation with anxiety, depression, and cognitive impairment in stroke patients
Autor: | Haifeng Ma, Qing Chang, Jujuan Jia, Yaoyuan Zhang, Gang Wang, Yuanyuan Li |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 56 (2023) |
Druh dokumentu: | article |
ISSN: | 1414-431X 1414-431x |
DOI: | 10.1590/1414-431x2023e12855 |
Popis: | Cell division cycle 42 (CDC42) regulates T helper (Th) cell differentiation and is related to psychological disorders. This study aimed to assess the correlation between blood CDC42 and Th cells, and their association with mental issues in stroke patients. Peripheral blood samples were obtained from 264 stroke patients and 50 controls. Then, serum CDC42 was measured by enzyme-linked immunosorbent assay, and Th1, Th2, and Th17 cells were detected by flow cytometry. Hospital Anxiety and Depression Scale (HADS) and Mini Mental State Examination (MMSE) were applied to patients. CDC42 was decreased (P |
Databáze: | Directory of Open Access Journals |
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