Cat-scratch disease manifesting as uveitis and binocular fundus nodular lesions: a case report

Autor: Hao Hong, Tianxi Li, Ye Ying, Qi An, Hu Liu, Kang Liang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Ophthalmology, Vol 23, Iss 1, Pp 1-6 (2023)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-023-03063-4
Popis: Abstract Background Cat-scratch disease typically presents with various ocular manifestations such as uveitis, vitritis, retinitis, retinochoroiditis, and optic neuritis. However, fundus nodular lesions was rarely reported. In our study, we reported a case of Cat-Scratch disease with binocular fundus nodular lesions. Case presentation An 11-year old male presented with uveitis in the right eye and bilateral fundus nodular lesions after indirect contact with unvaccinated cats. Comprehensive ancillary examinations including wide-angle fundus photography, ultrasonography, fluorescein fundus angiography, optical coherence tomography, and orbital magnetic resonance imaging were performed to elucidate the multidimensional features of the binocular lesions. Metagenomics next-generation sequencing was utilized to confirm the diagnosis of Cat-scratch disease. The patient’s condition showed improvement after a 6-month combination treatment regimen involving systemic administration of doxycycline hyclate and methylprednisolone tablets, as well as local application of mydriatic and corticosteroid eye drops. Conclusions We firstly reported a case of Cat-scratch disease presenting simultaneously with uveitis and fundus nodular lesions caused by Bartonella henselae infection in a child. Timely diagnosis and treatment with antibiotics and corticosteroids showed promising outcomes for the prognosis of these ocular disorders.
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