Iron-catalyzed indolo[2,3-c]quinoline synthesis from nitroarenes and benzylic alcohols/aldehydes promoted by elemental sulfur

Autor: Rong Li, Shuxin Jiang, Haolin Zheng, Hanwen Lei, Zhi Huang, Shanping Chen, Guo-Jun Deng
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Green Synthesis and Catalysis, Vol 3, Iss 1, Pp 95-101 (2022)
Druh dokumentu: article
ISSN: 2666-5549
DOI: 10.1016/j.gresc.2021.11.006
Popis: An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed. This cascade reaction involving alcohol oxidation, nitro reduction, and oxidative annulation was achieved in a one-pot. The present protocol was started from mono-functionalized indoles and readily available benzylic alcohols/aldehydes, affording a variety of functionalized indolo[2,3-c]quinolines in satisfactory yields.
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