High-flow nasal oxygenation during gastrointestinal endoscopy. Systematic review and meta-analysis

Autor: Michele Carron, Enrico Tamburini, Bijan Safaee Fakhr, Alessandro De Cassai, Federico Linassi, Paolo Navalesi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BJA Open, Vol 4, Iss , Pp 100098- (2022)
Druh dokumentu: article
ISSN: 2772-6096
DOI: 10.1016/j.bjao.2022.100098
Popis: Background: The use of high-flow nasal oxygen (HFNO) has the potential to improve patient safety by limiting hypoxaemia during gastrointestinal endoscopy. The degree of benefit is not adequately established. Methods: English language literature searches of PubMed, Scopus, Web of Science, and Cochrane Library electronic databases were performed to identify randomised controlled trials comparing HFNO and conventional oxygen therapy (COT) for patients undergoing gastrointestinal endoscopy under deep sedation. The primary endpoint was the incidence of hypoxic events observed during endoscopic procedures. The secondary endpoints were the incidence of recourse to rescue manoeuvres, procedure interruption, and adverse events. A meta-analysis and a post hoc trial sequence analysis were performed. Results: A total of 2867 patients from six randomised controlled trials were considered. Desaturation was observed in 5.2% and 27.2% of patients receiving HFNO and COT, respectively. Desaturation
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