First case report on Bickerstaff brainstem encephalitis in a young adult from Syria: Bridging clinical knowledge and practice

Autor: Ahmad Almohamed, Ayham Qatza, Haifa Alsamman, Suaad Hamsho, Mohammad Atia, Rahaf tamer, Almaya Mhd Ali, Waddah Kazkz
Jazyk: angličtina
Rok vydání: 2025
Předmět:
Zdroj: Radiology Case Reports, Vol 20, Iss 2, Pp 1211-1214 (2025)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2024.11.006
Popis: Bickerstaff Brainstem Encephalitis (BBE) is a rare immunologic condition characterized by CNS inflammation, presenting with ataxia, external ophthalmoplegia, altered consciousness, and quadriplegia. A 25-year-old male with no significant medical history exhibited symptoms of blurred vision, diplopia, facial numbness, and imbalance following a respiratory infection. Brain MRI revealed hyperintense lesions in the cerebral peduncle and pons on T2-weighted/FLAIR sequences but not on T1-weighted sequences, indicative of demyelination. Lumbar puncture showed clear cerebrospinal fluid with lymphocytic pleocytosis (80 cells/μl, 95% lymphocytes) and normal protein levels. The patient was treated with intravenous methylprednisolone (1000 mg/day for five days), resulting in recovery and normal follow-up MRI findings. Early diagnosis and treatment are crucial to minimize complications and improve outcomes. Additionally, airway management is essential for patients with impaired respiratory function, and long-term rehabilitation may be necessary for those recovering from encephalitis.
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