Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium

Autor: Erik Bakkeren, Ersin Gül, Jana S. Huisman, Yves Steiger, Andrea Rocker, Wolf-Dietrich Hardt, Médéric Diard
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29597-7
Popis: Salmonella Typhimurium virulence is costly and can be lost by mutation during infection. Bakkeren et al. show that virulence restoration via horizontal gene transfer is only transient while transmission bottlenecks promote long-term virulence stability.
Databáze: Directory of Open Access Journals