Trends in Incidence and Clinical Outcomes of Clostridioides difficile Infection, Hong Kong

Autor:	Cosmos L.T. Guo, Thomas N.Y. Kwong, Joyce W.Y. Mak, Lin Zhang, Grace C.Y. Lui, Grace L.H. Wong, Margaret Ip, Jun Yu, Joseph J.Y. Sung, William K.K. Wu, Sunny H. Wong
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Clostridioides difficile pseudomembranous colitis antimicrobial resistance epidemiology surveillance Hong Kong Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3036-3044 (2021)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2712.203769
Popis:	We conducted a territorywide survey to investigate the epidemiology, risk factors, and clinical outcomes of Clostridioides difficile infection (CDI) among hospitalized patients in Hong Kong. A total of 17,105 cases of CDI were identified, of which 15,717 (91.9%) were healthcare-associated and 1,025 (6.0%) were community-associated. Although CDI incidence increased substantially from 2006 to 2017, it plateaued in 2018 and 2019. The 30-day mortality rates decreased from 20.1% in 2015 to 16.8% in 2019, whereas the 60-day recurrence rates remained constant at ≈11% during the study period. Cross-correlation statistic showed significant correlations between incidence trend and overall antimicrobial drug use (r = 0.865, p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7b3b80364d4f489c88ddb93f61ac8ab3 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF