The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors

Autor: Sujun Chen, Jessica Petricca, Wenbin Ye, Jiansheng Guan, Yong Zeng, Nicholas Cheng, Linsey Gong, Shu Yi Shen, Junjie T. Hua, Megan Crumbaker, Michael Fraser, Stanley Liu, Scott V. Bratman, Theodorus van der Kwast, Trevor Pugh, Anthony M. Joshua, Daniel D. De Carvalho, Kim N. Chi, Philip Awadalla, Guoli Ji, Felix Feng, Alexander W. Wyatt, Housheng Hansen He
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-34012-2
Popis: Metastatic prostate cancer can be difficult to biopsy and characterise. Here, the authors use cell-free DNA methylation analysis to illustrate changes in hypermethylation in metastatic disease.
Databáze: Directory of Open Access Journals