Tratamento de vasculopatia livedóide com imunoglobulina intravenosa Treatment of Livedoid Vasculopathy with intravenous immunoglobulin
| Autor: | Jader Freire Sobral Filho, Milane Caroline de Oliveira Valdek, Luiza Toscano Dias Rodrigues |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Anais Brasileiros de Dermatologia, Vol 83, Iss 4, Pp 372-374 (2008) |
| Druh dokumentu: | article |
| ISSN: | 0365-0596 1806-4841 |
| DOI: | 10.1590/S0365-05962008000400014 |
| Popis: | A vasculopatia livedóide apresenta-se com dor e úlceras de cicatrização lenta em membros inferiores, e fisiopatologia obscura. As estratégias terapêuticas incluem cicatrizantes, antiinflamatórios e imunossupressores, sem relatos de benefício permanente. Administrou-se imunoglobulina em paciente refratário a outras terapias e avaliou-se o comprometimento da pele antes e depois por meio de escore clínico. Houve regressão significativa das lesões. A droga foi bem tolerada, e a terapia foi finalizada.Livedoid vasculopathy presents with pain and slowly healing ulcerations of the lower limbs, and has obscure pathophysiology. Usual therapeutics include rheologic, anti-inflammatory and immunosuppressing agents with no reports of permanent benefits. Immunoglobulin was administered to a patient who was refractory to other treatments and skin involvement was assessed by means of clinical score before and after treatment. There was a significant healing of the lesions. Imunoglobulim was well tolerated and therapy was discontinued. |
| Databáze: | Directory of Open Access Journals |
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