| Autor: |
S. V. K. R. Rajeswari, Vijayakumar Ponnusamy, Nemanja Zdravkovic, Emilija Kisic, V. Padmajothi, S. Vijayalakshmi, C. Anuradha, D. Malathi, Nandakumar Ramasamy, Kumar Janardhan, Melvin George |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-024-78144-5 |
| Popis: |
Abstract Diabetic Peripheral Neuropathy (DPN) is a nerve damage that is treated with painkillers and steroids which have the drawback of interference with other medications and the dangers of side effects. Novelty of the proposed work is to develop a Near Infrared Region (NIR) based non-invasive therapy device called ‘DPNrelief-1.0V’developed with a 890 nm wavelength diodes. DPNrelief-1.0V delivers a total dosage of 6.174 J/cm2 with heat absorption by tissue of 61.74 Joules at 30 minutes. The device was tested by carrying out a pilot study with 8 patients where 4 were treatment group and control group. The DPNrelief-1.0V is validated by Nerve Conduction Study (NCS) test. The degenerated nerves pre-therapy showed less amplitude, Conduction Velocity (CV) and latency which was improved post-therapy by 100% in amplitude of nerve signal, 100% in CV and a decrease of 36.2% in latency. Independent t-test was conducted to find the difference between control and treatment, wherein a p value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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