Potential Application of Quantitative Prostate-specific Antigen Analysis in Forensic Examination of Seminal Stains

Autor: Zhenping Liu, Yang Yang, Zhikan Pan, Xiaoxu Zhu, Shi Feng, Dong Zhao
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Forensic Science and Medicine, Vol 1, Iss 2, Pp 159-162 (2015)
Druh dokumentu: article
ISSN: 2349-5014
DOI: 10.4103/2349-5014.169640
Popis: The aims of this study are to use quantitative analysis of the prostate-specific antigen (PSA) in the seminal stain examination and to explore the practical value of this analysis in forensic science. For a comprehensive analysis, vaginal swabs from 48 rape cases were tested both by a PSA fluorescence analyzer (i-CHROMA Reader) and by a conventional PSA strip test. To confirm the results of these PSA tests, seminal DNA was tested following differential extraction. Compared to the PSA strip test, the PSA rapid quantitative fluorescence analyzer provided the more accurate and sensitive results. More importantly, individualized schemes based on quantitative PSA results of samples can be developed to improve the quality and procedural efficiency in the forensic seminal inspection of samples prior to DNA analysis.
Databáze: Directory of Open Access Journals