Exercise intensity and mortality in overweight and obese patients with chronic kidney disease: longitudinal analysis (1999–2016)

Autor: Chuyue Qian, Fengjun Zhou, Dandan Lu, Jingda Huang, Mindan Sun
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-024-20498-6
Popis: Abstract Background Chronic kidney disease (CKD) and overweight/obesity are significant global public health issues. Appropriate free-time physical activity (PA) is essential for overweight/obese patients with chronic kidney disease, but specific guidelines are lacking. The present study was conducted to determine the association between PA and all-cause mortality in these patients. Methods Data from 3,434 overweight/obese adults with CKD from the 1999–2016 National Health and Nutrition Examination Surveys were analyzed. Associations between clinical/laboratory findings and PA intensity (moderate and vigorous) were investigated. The all-cause mortality of patients in different PA categories were compared by Kaplan–Meier analysis. Factors associated with all-cause mortality were determined using a Cox proportional hazards model. A restricted cubic spline was employed to obtain a more flexible and detailed representation of the relationship between PA intensity and all-cause mortality, with better predictive capability. Results The Kaplan–Meier analysis revealed that greater all-cause mortality was associated with
Databáze: Directory of Open Access Journals
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