Burden of Severe Acute Respiratory Syndrome Coronavirus 2 and its Seasonal Trends in Patients Attending a Tertiary Healthcare Centre in Rajasthan: A Retrospective Observational Study

Autor: M Anjaneya Swamy, Shweta Bohra, Jagannath Dnyanoba Andhale, Megha Sharma, Anjali Kulshreshtha
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 17, Iss 11, Pp 10-15 (2023)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2023/64207.18729
Popis: Introduction: The pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has drastically affected the global population, leading to high rates of morbidity and mortality. This virus originated in China had quickly spread to different countries worldwide, paralysing healthcare systems. Alongside supportive therapy, isolation, and contact tracing, vaccines have also played a crucial role in rescuing the human population from the virus. Aim: To evaluate the burden of SARS-CoV-2 and its seasonal trends. Materials and Methods: This retrospective observational study was conducted in the Department of Microbiology at the Ananta Institute of Medical Sciences and Research Centre in Rajsamand, Rajasthan, India. Data was collected from July 2020 to September 2022 and analysed from January 2023 to March 2023. The study included a sample size of 14,050. Nasopharyngeal and throat swab samples were collected into a single tube of Viral Transport Medium (VTM). Ribonucleic Acid (RNA) was extracted from the VTM, and real-time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) was performed using different kits approved by the Indian Council of Medical Research (ICMR). Results were interpreted according to the manufacturer’s instructions. A Chisquared test was performed using GraphPad Prism version 9.2.0.332. A p-value of
Databáze: Directory of Open Access Journals