Multi-Component Syntheses of Spiro[furan-2,3′-indoline]-3-carboxylate Derivatives Using Ionic Liquid Catalysts

Autor:	Mehdi Khalaj, Maryam Zarandi, Malihe Samadi Kazemi, Seyed Mahmoud Musavi, Johannes Hohnsen, Axel Klein
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	spiro[furan-2 3′-indoline]-3-carboxylate derivatives ionic liquid catalyst butenolides spiro compounds imidazolium hydrogen sulfate pyridinium hydrogen sulfate Organic chemistry QD241-441
Zdroj:	Molecules, Vol 29, Iss 6, p 1223 (2024)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules29061223
Popis:	Two previously described Brønsted acidic ionic liquids, 3,3′-(1,6-hexanediyl)bis(1-methyl)-1H-imidazolium hydrogen sulfate (Cat1) and 1,1′-(1,6-hexanediyl)bis(pyridinium) hydrogen sulfate (Cat2), were used as catalysts for the preparation of spiro[furan-2,3′-indoline]-3-carboxylate derivatives via a three-component reaction of anilines, isatins (N-alkyl-indoline-2,3-diones), and diethyl acetylenedicarboxylate, in high yields. The use of ultrasonic (US) irradiation led to the targeted products (1a–15a) in high yields ranging from 80% to 98%. Under the same conditions, the use of sulfuric acid and acetic acid as a Brønstedt catalyst did not yield the desired benchmark product 1a.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7ab6eadd4bb24008a5328b1c2999bf4a Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.