| Autor: |
Christopher Torrens, Priya Ethirajan, Kimberley D Bruce, Felino R A Cagampang, Richard C M Siow, Mark A Hanson, Christopher D Byrne, Giovanni E Mann, Geraldine F Clough |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 7, Iss 12, p e50671 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0050671 |
| Popis: |
To determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring.Female C57BL6J mice were fed an obesogenic high fat diet (HF, 45% kcal fat) or standard chow (C, 21% kcal fat) pre-conception and throughout pregnancy and lactation. Post-weaning, male offspring were continued on the same diet as their mothers or placed on the alternative diet to give 4 dietary groups (C/C, HF/C, C/HF and HF/HF) which were studied at 15 or 30 weeks of age.There were significant effects of maternal diet on offspring body weight (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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