Joint morphogenetic cells in the adult mammalian synovium

Autor: Anke J. Roelofs, Janja Zupan, Anna H. K. Riemen, Karolina Kania, Sharon Ansboro, Nathan White, Susan M. Clark, Cosimo De Bari
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms15040
Popis: The stem cells that maintain and repair adult joint tissues in mammals, including articular cartilage, remain incompletely defined. Here the authors perform lineage tracing studies in adult mice and find an ontogenetically defined progenitor cell population that is functional in the synovial joint and distinct from previously reported mesenchymal stem cell populations.
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