Bone angiosarcoma in the humerusof a pediatric patient, a whole diagnosticchallenge: Case report

Autor: Bravo-Luna, Lucy
Jazyk: Spanish; Castilian
Rok vydání: 2022
Předmět:
Zdroj: Iatreia, Vol 35, Iss 2, Pp 193-199 (2022)
Druh dokumentu: article
ISSN: 0121-0793
2011-7965
DOI: 10.17533/udea.iatreia.118
Popis: Angiosarcoma of the bone is a rare, aggressive and poor-prognosis malignancy, that is unusual in children. This entity preferentially affects the tubular bones, and can present as a solitary or multicentric lesion. We present the case of a 7-year-old girl, without medical surgical history, who consulted to the National Cancer Institute - Colombia, for presenting a tumor lesion that compromised the entire humerus, destroying it and deforming the arm. To guide the diagnosis of the lesion, a detailed histopathological study and immunohistochemical markers were performed, which suggested a malignant vascular neoplasm. Due to the extensive tumor involvement, the only therapeutic option was scapulothoracic disarticulation of the limb, followed by adjuvant management with a chemotherapy protocol. During the chemotherapy cycles, the patient presented metastatic lesions in the lung, which were resected. At the moment, she is without tumor lesions and under close follow-up.
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