Hepatic decompensation associated with an interferon-free antiviral therapy in patients with HCV-cirrhosis

Autor:	S N Batskikh, E V Vinnitskaya, Yu G Sandler, T Yu Khaimenova
Jazyk:	ruština
Rok vydání:	2018
Předmět:	hepatitis c cirrhosis antiviral therapy direct-acting antiviral agents decompensation Medicine
Zdroj:	Терапевтический архив, Vol 90, Iss 11, Pp 67-73 (2018)
Druh dokumentu:	article
ISSN:	0040-3660 2309-5342
DOI:	10.26442/terarkh201890114-73
Popis:	Today, there is no complete clarity about the pathogenetic mechanisms of the hepatic decompensation in patients with HCV-cirrhosis during the course of direct-acting antiviral (DAAs) therapy. The current article describes several clinical observations of decompensation (with the development of liver failure and portal hypertension) in cirrhotic patients during the course of DAAs-therapy of hepatitis C. The authors present contemporary views and their own assumptions about the possible mechanisms of the hepatic decompensation associated with DAAs-therapy in patients with liver cirrhosis.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7a8b5c65fa664170bdc11cacf64837dc Zobrazit plný text záznamu View record in DOAJ