A Magnetically Tunable Check Valve Applied to a Lab-on-Chip Nitrite Sensor

Autor: Sean C. Morgan, Andre D. Hendricks, Mae L. Seto, Vincent J. Sieben
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Sensors, Vol 19, Iss 21, p 4619 (2019)
Druh dokumentu: article
ISSN: 1424-8220
DOI: 10.3390/s19214619
Popis: Presented here is the fabrication and characterization of a tunable microfluidic check valve for use in marine nutrient sensing. The ball-style valve makes use of a rare-earth permanent magnet, which exerts a pulling force to ensure it remains passively sealed until the prescribed cracking pressure is met. By adjusting the position of the magnet, the cracking pressure is shown to be customizable to meet design requirements. Further applicability is shown by integrating the valve into a poly(methyl methacrylate) (PMMA) lab-on-chip device with an integrated optical absorbance cell for nitrite detection in seawater. Micro-milling is used to manufacture both the valve and the micro-channel structures. The valve is characterized up to a flow rate of 14 mL min−1 and exhibits low leakage rates at high back pressures (−1 at ~350 kPa). It is low cost, requires no power, and is easily implemented on microfluidic platforms.
Databáze: Directory of Open Access Journals
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