Melatonin enhances the developmental potential of immature oocytes from older reproductive-aged women by improving mitochondrial function

Autor: Dandan Yang, Yaoqin Mu, Jing Wang, Weiwei Zou, Huijuan Zou, Han Yang, Chao Zhang, Yongqi Fan, Heng Zhang, Huan Zhang, Beili Chen, Zhiguo Zhang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Heliyon, Vol 9, Iss 9, Pp e19366- (2023)
Druh dokumentu: article
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2023.e19366
Popis: Aims: To evaluate whether melatonin (MT) supplementation during in vitro maturation (IVM) of human oocytes can reverse the age-related decline in oocyte quality. Main methods: We enrolled 172 patients aged ≥35 years (older reproductive-aged women) and 83 patients aged
Databáze: Directory of Open Access Journals