Effects of black raspberry, blueberry, and blackberry volatile extracts on intestinal barrier dysfunction and inflammation in a Caco-2/RAW264.7 cells co-culture model

Autor:	Inah Gu, Cindi Brownmiller, Luke Howard, Sun-Ok Lee
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Black raspberry volatiles Blueberry volatiles Blackberry volatiles Intestinal inflammation Intestinal barrier dysfunction Caco-2/RAW264.7 cell co-culture Nutrition. Foods and food supply TX341-641
Zdroj:	Journal of Functional Foods, Vol 114, Iss , Pp 106069- (2024)
Druh dokumentu:	article
ISSN:	1756-4646
DOI:	10.1016/j.jff.2024.106069
Popis:	Berry volatiles are responsible for the aroma of berries. However, their impacts on intestinal inflammation are unclear. Thus, this study investigated the effects of black raspberry, blueberry, and blackberry volatile extracts (BVEs) on intestinal barrier dysfunction and inflammation using a Caco-2/RAW264.7 cells co-culture model. BVE treatments significantly enhanced integrity and decreased permeability in LPS-damaged epithelial monolayers with increased tight junctions. Blueberry and blackberry volatile extract treatments significantly inhibited the LPS-induced overproduction of NO, IL-6, and TNF-α (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d7a58f196d9c45c6bc65bd24d68f8a0f Zobrazit plný text záznamu Full Text from ScienceDirect View record in DOAJ