Detection of human parvovirus B19 in serum samples from children under 5 years of age with rashâfever illnesses in the Democratic Republic of the Congo

Autor: Tony Bokalanga Wawina, Olivier Mbaya Tshiani, Steve Mundeke Ahuka, Elisabeth Simbu Pukuta, Michel Ntetani Aloni, Christopher Jacob Kasanga, Jean-Jacques Tamfum Muyembe
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 65, Iss , Pp 4-7 (2017)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2017.09.018
Popis: Background: It has been demonstrated that infection with human parvovirus B19 (B19V) is associated with rashâfever illnesses. The present study aimed to investigate B19V as an aetiological agent of rashâfever syndromes in Congolese children confirmed as measles and rubella IgM-negative. An ELISA IgM test and PCR were performed to screen for B19V. Methods: A total of 177 archived serum samples were randomly selected from the measles biobank of the National Institute for Biomedical Research (INRB). Samples were investigated for anti-B19V IgM and B19V DNA. These samples originated from children
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