| Autor: |
Yilmaz Bilgic, Murat Harputluoglu, Bulent Yaprak, Mehmet Burak Dal, Mehmet Bugra Bozan, Abdurrahman Sahin, Fatih Mehmet Yazar, Yasir Furkan Cagin, Nihat Okcu |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Medicine Science, Vol 4, Iss 4, Pp 2772-81 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2147-0634 |
| DOI: |
10.5455/medscience.2015.04.8283 |
| Popis: |
In the present study, we investigated the relationship between serum TNF-α levels and hepatic activity in liver biopsies of chronic hepatitis B and C patients.The study was performed on 30 chronic hepatitis B patients, 25 chronic hepatitis C patients and 25 healthy controls. Serum samples of patients who underwent biopsy and healthy controls were collected. Control group was seronegative for hepatitis and had normal liver function tests. TNF- α levels measured by ELISA. Knodells hepatic activity index was used in evaluation of liver biopsies. Serum TNF-α levels were determined higher in chronic hepatitis B and C patients than control group. HAI and TNF- α compared in chronic hepatitis B and C patients. Although we detected a relationship between HAI and TNF-α levels in chronic hepatitis B patients, no true correlation was shown in chronic hepatitis C patients. Cytokines have an important role in progression of chronic hepatitis B and C infections. There is a relationship between hepatic activity index and TNF-α level in chronic hepatitis B infection.But There is not relationship between hepatic activity index and chronic hepatitis C infection.only in two patients and both of them where in the middle of their reproductive age while as symptomatic ovarian cysts was a more common finding in unmarried females in 21-28 years of age group. This study concluded that laparoscopy has a diagnostic as well as a therapeutic implication in management of NSAP. [Med-Science 2015; 4(4.000): 2772-81] |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
