Surgical management of sarcoma in adolescent and young adult patients

Autor: Kazuhiko Hashimoto, Shunji Nishimura, Naohiro Oka, Masao Akagi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Research Notes, Vol 13, Iss 1, Pp 1-7 (2020)
Druh dokumentu: article
ISSN: 1756-0500
DOI: 10.1186/s13104-020-05107-0
Popis: Abstract Objective To examine the clinical features and outcomes of adolescent and young adult sarcoma patients who underwent surgical management and clarify important factors associated with prognosis. We reviewed 18 young adult sarcoma patients sarcoma patients treated surgically in our hospital. The tumor site, histology, grade, stage, and American Society of Anesthesiologists-Physical Status before surgery, operation time, intraoperative blood loss, complications, surgical margin, local recurrence, metastasis, and outcomes were investigated. The 3-year survival rate was also calculated. We compared survival based on age, grade, and surveyed features of poor outcome cases. Results The 3-year survival rate was 61.3%. There was no significant difference in survival based on age, grade, operation time, or intraoperative blood loss. Three of five patients who died of the disease had stage ≥ IV at diagnosis. All patients with R1 surgical margins developed recurrence and all those with an American Society of Anesthesiologists-Physical Status ≥ 2 died. Patients with late-stage sarcomas, R1 tumor margin, or high American Society of Anesthesiologists-Physical Status score had poor prognoses. To achieve a favorable outcome in adolescent and young adult sarcoma patients, early detection and obtaining R0 ≥ surgical margin are essential.
Databáze: Directory of Open Access Journals
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