Epidemiology of COVID-19 in Mexico: Symptomatic profiles and presymptomatic people

Autor: Miguel A. Fernández-Rojas, Marco A. Luna-Ruiz Esparza, Abraham Campos-Romero, Diana Y. Calva-Espinosa, José L. Moreno-Camacho, Ariadna P. Langle-Martínez, Abraham García-Gil, Claudia J. Solís-González, Adrián Canizalez-Román, Nidia León-Sicairos, Jonathan Alcántar-Fernández
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 104, Iss , Pp 572-579 (2021)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2020.12.086
Popis: Objectives: The COVID-19 diagnosis is difficult and ambiguous due to nonspecific symptoms. Further, data from Mexico arehospitable population-based without signs and symptoms information. Thus, this work aims to provide epidemiology information about the burden of COVID-19 in Mexican outpatients and to identify symptomatic COVID-19 profiles that could help in the early diagnosis of the disease. Methods: From June to September, epidemiological, clinical, and demographic data of 482,413 individuals diagnosed by RT-PCR test for SARS-CoV-2 in Salud Digna clinics were collected. Results: We observed a 41% incidence of SARS-CoV-2 infections with a mean age of 36 years and with young adults (20–40 years) being the most affected. Among occupations, delivery persons (OR 1.38) or informal traders (OR 1.33) had a higher risk of COVID-19. Moreover, 13% of SARS-CoV-2 infections were in presymptomatic patients. Finally, we identified three different symptomatic profiles (common, respiratory, and gastrointestinal) associated with COVID-19. Conclusion: The incidence of SARS-CoV-2 was high among outpatients with a significant proportion of presymptomatic carriers, and thus it is necessary to increase testing and continue SARS-CoV-2 surveillance with a better description of signs and symptoms; in this regard, we identified three symptomatic profiles that could help in the diagnosis of COVID-19.
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