| Autor: |
P. Mantero, L. Marchesi Olid, C Giacomantone, A. Cabanne, M. Zubillaga, M. Blaser, M. Janjetic, C. Goldman |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Microbiota in Health and Disease, Vol 5 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2704-8845 |
| DOI: |
10.26355/mhd_202311_950 |
| Popis: |
Objective: Ghrelin is an appetite-modulating peptide mainly produced in the stomach, with levels reported to be lower in Helicobacter pylori-positive subjects. This pre-post study aimed to evaluate the effect of H. pylori eradication on circulating total ghrelin, gastric histopathology, appetite, and nutritional status of dyspeptic adults. Patients and Methods: Weight, height, appetite and nutrient intake were determined using validated tools. Gastric biopsies were obtained for histopathology and H. pylori diagnosis. Fasting serum ghrelin was measured by ELISA. H. pylori-positive subjects received eradication therapy and returned ≥12 weeks later for re-evaluation. Results: Of 117 screened individuals, 47 who were H. pylori-positive were included, and the organism was eradicated in 28 (59.6%). Pathologic findings decreased significantly after treatment in subjects with eradication (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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