Comparison of non-electrophoresis grade with electrophoresis grade BIS in NIPAM polymer gel preparation
| Autor: | Roghaye Khodadadi, Azim Khajeali, Alireza Farajollahi, Parisa Hajalioghli, Noorallah Raeisi |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | BioImpacts, Vol 5, Iss 3, Pp 129-133 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2228-5652 2228-5660 |
| DOI: | 10.15171/bi.2015.16 |
| Popis: | Introduction: The main objective of this study was to investigate the possibility of replacing electrophoresis cross-linker with non-electrophoresis N, N′-methylenebisacrylamide (BIS) in N-isopropyl acrylamide (NIPAM) polymer gel and its possible effect on dose response. Methods: NIPAM polymer gel was prepared from non-electrophoresis grade BIS and the relaxation rate (R2) was measured by MR imaging after exposing the gel to gamma radiation from Co-60 source. To compare the response of this gel with the one that contains electrophoresis grade BIS, two sets of NIPAM gel were prepared using electrophoresis and non-electrophoresis BIS and irradiated to different gamma doses. Results: It was found that the dose–response of NIPAM gel made from the non-electrophoresis grade BIS is coincident with that of electrophoresis grade BIS. Conclusion: Taken all, it can be concluded that the non-electrophoresis grade BIS not only is a suitable alternative for the electrophoresis grade BIS but also reduces the cost of gel due to its lower price. |
| Databáze: | Directory of Open Access Journals |
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