| Autor: |
Zhaoyun Ding, Ting Cai, Jupei Tang, Hanxiao Sun, Xinyi Qi, Yunpeng Zhang, Yan Ji, Liyun Yuan, Huidan Chang, Yanhui Ma, Hong Zhou, Li Li, Huiming Sheng, Ju Qiu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-022-35250-0 |
| Popis: |
Treg cells can be functionally altered by epigenetic modulators. Here the authors show that the histone H3K36 methyltransferase Setd2 is important for the survival of Treg cells and for the regulation of IL-33 mediated Th2 responses in mice and SETD2 expression is increased in Treg cells from human colorectal cancer tissue. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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