| Autor: |
Ayush Agarwal, Jyoti Sharma, M. V. Padma Srivastava, M. C. Sharma, Rohit Bhatia, Deepa Dash, Vinay Goyal, Achal K. Srivastava, Manjari Tripathi, Vaishali Suri, Mamta B. Singh, Sushant Agarwal, Chitra Sarkar, Leve Joseph, Manmohan Singh, Ashish Suri, Rajesh K. Singh, Deepti Vibha, Awadh K. Pandit, Roopa Rajan, Anu Gupta, A. Elavarasi, Divya M. Radhakrishnan, Animesh Das, Shailesh Gaikwad, Vivek Tandon, Ramesh Doddamani, Ashish Upadhyay, Ajay Garg, Venugopalan Y. Vishnu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-022-17869-7 |
| Popis: |
Abstract Primary CNS Vasculitis (PCNSV) is a rare inflammatory disorder affecting the blood vessels of the central nervous system. Patients present with a combination of headaches, seizures, and focal neurological deficits. There is usually a diagnostic delay. Treatment is based on observational studies and expert opinion. Our objective was to identify clinical, laboratory, neuroimaging, pathologic or management-related associations with 2 year outcome in patients with primary CNS vasculitis. We conducted a cohort study at a single tertiary care referral centre of prospectively (2018-2019) and retrospectively (2010-2018) identified individuals with primary CNS vasculitis (diagnosis was proven by either brain biopsy or cerebral digital subtraction angiography). Clinical, imaging and histopathologic findings, treatment, and functional outcomes were recorded. Univariate and stepwise multiple logistic regression were applied. P-value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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