Long-term immunogenicity after measles vaccine vs. wild infection: an Italian retrospective cohort study

Autor:	Francesco Paolo Bianchi, Simona Mascipinto, Pasquale Stefanizzi, Sara De Nitto, Cinzia Germinario, Silvio Tafuri
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	long time immunogenicity measles elimination era natural booster additional booster healthcare workers Immunologic diseases. Allergy RC581-607 Therapeutics. Pharmacology RM1-950
Zdroj:	Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 2078-2084 (2021)
Druh dokumentu:	article
ISSN:	2164-5515 2164-554X 21645515
DOI:	10.1080/21645515.2020.1871296
Popis:	The persistence of specific IgG after measles infection and after measles vaccination has not been sufficiently investigated. Current evidence suggests that immunity after the disease is life-long, whereas the response after two doses of measles-containing vaccine declines within 10–15 years. This study evaluated the proportion of individuals with detectable anti-measles IgG in two groups, those vaccinated with two doses of anti-MMR vaccine and those with a self-reported history of measles infection. Among the 611 students and residents who were tested, 94 (15%) had no detectable protective anti-measles IgG. This proportion was higher among vaccinated individuals (20%; GMT = 92.2) than among those with a self-reported history of measles (6%; GMT = 213.3; p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/c79e402f5c1849c592392f578d56e91c Zobrazit plný text záznamu View record in DOAJ