| Autor: |
Wanze Chen, Petra C. Schwalie, Eugenia V. Pankevich, Carine Gubelmann, Sunil K. Raghav, Riccardo Dainese, Marco Cassano, Michael Imbeault, Suk Min Jang, Julie Russeil, Tenagne Delessa, Julien Duc, Didier Trono, Christian Wolfrum, Bart Deplancke |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-09803-9 |
| Popis: |
Although Krüppel-associated box zinc finger proteins (KZFPs) were found to mostly repress transposable elements, recent studies found that KFZPs also play other roles in cells. Here, the authors provide evidence that the KZFP ZFP30 promotes adipogenesis by targeting and activating a retrotransposon-derived Pparg2 enhancer in cooperation with co-regulator KRAB-associated protein 1 (KAP1). |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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